eMedinewS Editorial

Health Care 69 Comments

Drug–eluting versus bare–metal stents

In patients with large coronary arteries, the absolute benefit (a lower rate of restenosis) from drug–eluting stent (DES) compared to bare–metal stents (BMS) is small due to the low rate of restenosis in these vessels. Thus, any difference in safety may be important in choosing one or the other stent type.

The BASKET–PROVE trial randomly assigned 2314 patients needing stents 3.0 mm or greater in diameter to one of two different DES or to BMS. The rate of the primary endpoint (composite of death from cardiac causes or nonfatal myocardial infarction at two years) was lower, but not significantly so, with either of the two DES.

Dr KK Aggarwal
Editor in Chief