eMedinewS Editorial

4:47 am Health Care

Cilostazol for prevention of ischemic stroke

The antiplatelet agent cilostazol is a phosphodiesterase 3 inhibitor that is used mainly to treat intermittent claudication in patients with peripheral artery disease. Several controlled trials in Asia have found that cilostazol is effective for the secondary prevention of cerebral infarction.

In the largest such trial (CSPS II), cilostazol (100 mg twice daily) was not inferior to aspirin (81 mg daily) in preventing recurrent stroke (infarction or hemorrhage) at a mean follow–up of 29 months in 2757 patients in Japan with a recent noncardioembolic cerebral infarction.

Dr KK Aggarwal
Editor in Chief

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