CMAAO Coronavirus Facts and Myth Buster: Mortality Score

Health Care Comments Off

With input from Dr Monica Vasudev

4C mortality score predicts mortality in hospitalized patients with COVID-19

4C (Coronavirus Clinical Characterisation Consortium) Mortality Score can be used to accurately categorize patients hospitalized with coronavirus disease 2019 (COVID-19) as being at low, intermediate, high, or very high risk of death, according to a study published in The BMJ.

The 4C Mortality Score uses 8 variables — age, sex, number of comorbidities, respiratory rate, peripheral oxygen saturation, level of consciousness, urea level, and C reactive protein — to calculate a score that ranges from 0 to 21 points.

0 – 3: Low risk of mortality
4 to 8: Intermediate risk
9 to 14: High risk
≥15: Highest mortality risk.
[British Medical Journal]

Variable

4C Mortality Score

Age (years)

<50

50-59

+2

60-69

+4

70-79

+6

≥80

+7

Sex at birth

Female

Male

+1

No of comorbidities*

0

1

+1

≥2

+2

Respiratory rate (breaths/min)

<20

20-29

+1

≥30

+2

Peripheral oxygen saturation on room air (%)

≥92

<92

+2

Glasgow coma scale score

15

<15

+2

Urea (mmol/L)

≤7 ( 20 mg/dL)

7-14

+1

>14 ( 40 mg/dL)

+3

C-reactive protein (mg/dL)

<50

50-99

+1

≥100

+2

* Comorbidities were defined by using Charlson comorbidity index, with the addition of clinician defined obesity.

Dr KK Aggarwal

President CMAAO, HCFI and Past National President IMA