Anti-nausea drug ondansetron linked to arrhythmias

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Ondansetron can trigger dangerous and possibly lethal changes in heart rhythms as per FDA warning. It can cause prolongation of the QT interval in ECG which can lead to an abnormal and potentially fatal heart rhythm, including Torsade de Pointes,” the FDA said.

Patients at greatest risk include those with “underlying heart conditions, such as congenital long QT syndrome, [and] those who are predisposed to low levels of potassium and magnesium in the blood” as well as patients who are taking other medications also associated with QT prolongation.

Ondansetron is a 5-HT3 serotonin receptor antagonist, commonly prescribed to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery.

The FDA label recommend ECG monitoring in certain patients including those with hypokalemia or hypomagnesemia, congestive heart failure, bradyarrhythmias, and in patients who are taking other medications that increase the risk of QT.

The science behind observing Shradhs

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Shradhs are observed every year in Dakshinayana during Chaturmas in the Krishna Paksha of Ashwin month. Many rituals are performed to satisfy the unfulfilled desires of three generations of our ancestors.

According to the Vedas, every individual has three debts to be paid off, firstly, the Devtas (Dev Rin), secondly of Guru and teachers (Rishi Rin) and, thirdly, of Ancestors (Pitra Rin).  From the scientific point of view, devtas represent people with Daivik qualities; teachers the ones who have taught us and Pitra, three generations of our ancestors. ‘Rin’ from scientific point of view would mean unfinished desires or tasks.

The rituals scientifically would mean detaching oneself from the guilt of unfinished task of our ancestors by detoxifying our mind.

Debt means desires of our ancestors that had not fulfilled during their lifetime. The responsibility to fulfill them automatically falls onto the eldest son in the family and they need to be carried out. If not, it is a sign of guilt disorder in the family and may present with loss of wealth, loss of direction and courage and health. The resultant problems faced were called Pitra Dosh in mythology.

The ritual of performing Shradhs originated to remove this guilt and the resultant illnesses. Shradh has many components.

  • Tarpan (offering water to the ancestors while reciting Mantras).
  • Arpan (preparing food what the ancestors used to like on the day of Shradh)
  • Brahmin bhoj (offering Satvik food to Brahmins)
  • Pind Daan (offering black sesame, Kusha Grass, Jwar and boil or baked rice); observed by some.
  • Observing a spiritual holiday or incubation period (taking a break from the routine worldly desires and going to a distant place like Gaya).
  • Remembrance: Once the unfulfilled desires of the ancestors are over, remembering our ancestors every year on the day of their death anniversary.

Scientifically, Dakshinayana is the period of negative state of mind (nights are longer than days) and starts from 14th July and ends on 13th January. Chaturmas period (first four months) during Dakshinayana has the maximum negativity in the mind. Chaturmas includes the months of Sawan, Bhado, Ashwin and Kartik.

The negative state of mind in Sawan is related to anger and disturbed mind; in Bhado to non fulfillment of desires and uncontrolled ego and in the month of Ashwin to guilt because of non fulfillment of desires of others (ancestors), especially during Amavasya.

In the rituals ‘Tarpan’ of Jal (water) is offered to ancestors. ‘Jal’ in mythology means flow of thoughts and offering ‘Jal’ in mythology equates to confession and getting connected. Tarpan is always done with an aim to purify the mind and wash off the guilt.

‘Tarpan’ is always done after the desires of our ancestors have been fulfilled by the person performing the Shradh. This ritual is ‘Arpan’. Tarpan and Arpan on the day of Shradh mean getting connected to our consciousness and informing that all the unfinished tasks are over so that we can get rid of the long persisting guilt from our mind. Offering and making food which was liked by our ancestors on that day is just to remember and pay respect to them.

Confession is only possible in a Satwik state of mind, which requires eating of Satwik food for a few days. The ritual of offering Satwik food to Brahmins during the Shradh means making only Satwik food on that day so that everyone in the family is forced to eat Satwik food during Shradhs.

Pind Daan denotes medicinal ways of detaching oneself from the guilt. All the four offerings (black sesame, Kusha grass, Jwar and boiled or roasted rice) in Ayurveda have been described to detoxify the mind and making it Satwik by removing Rajas and Tamas.

If the guilt does not go by repeated Shradhs than one is required to go for a spiritual vacation during Shradh period so that he is away from the worldly desires for a few days before the Shradh and this is what going to Gaya means. This spiritual retreat works like an incubation period to the disturbed mind and gets rid off the disturbed mind and allows the undisturbed state of mind to confess and purify.

The Pitra ceremonies are usually performed either on Amavasya every month (period of most negativity in a month) or on the death anniversary or the Hindu Tithi (day) of the death of the ancestors coinciding with the day during Shradh days. If the date of death is not known then the Shradh is observed on Amavasya.

Some people perform Shradh for full 15 days and others perform it from the first day till the day of their ancestor Shradh.

It is said that once a Shradh is successfully performed or Gaya Shradh is performed, there is no need to perform Shradh rituals thereafter. Once the guilt is over, there is no need for further detoxification of the mind. After that the only ritual that needs to be performed is ‘remembrance”, which is usually performed on the death anniversary of the deceased ancestor usually by doing some charity on their names.

One is not supposed to do auspicious things during Shradh as during this period, the mind is in a process of detoxification.

Go wish your Muslim friend Eid Mubarak

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Once I was listening to a scholar who was trying to find out why Hindu and Muslims fight with each other.  He narrated that Muslims want their ‘Ali’ back from “Diwa-li” and Hindus want their ‘Rama’ back from “Rama-dan”.

Eid is observed in Islam twice in a year, once it is observed as Sevainyan Eid (Eid ul-Fitr) and the other as Bakra Eid (Eid-al-adha ).

Eid ul Fitr marks the end of Ramadan, the Islamic holy month of fasting.  Eid is an Arabic word meaning “festivity,” while Fiá¹­r means “breaking (the fast)”. Ramadan is thirty days of dawn-to-sunset fasting.
Thirty days of Ramadan in Islam; nine days of Navratra in Hinduism and forty days of Easter in Christianity are spiritual practices observed by respective religions. These are days of mind, body and soul detoxification observed as per religion defined rituals. Broadly, they involve restraining the ten senses during the fast period. One restrains from negative thoughts cum actions and indulges in positive thoughts cum actions.

In Ramadan, one month continuous fast detoxifies the mind, body and soul and reenergizes the human being.

Eid ul Fitr is observed as general detoxification process of the mind, body and soul. Eid-al-adha on the other hand is based on observing “detached attachment” where a person leans to sacrifice (detachment) a goat after practiced attachment for few months.

On the day of Eid, people wear new clothes and also care for the poor and the needy. They also offer prayers and seek Allah help for forgiving their sins and make them pure and pious human beings.

In Ramadan, Muslims fast and increase their spiritual devotions, and recognize their spiritual powers. On Eid Muslims thank Allah for the gift of fasting, in which they avoid food and drink from dawn to dusk. The Prophet Muhammad said, “Whoever fasts the month of Ramadan out of faith, seeking its reward, shall have all their past sins forgiven.”

‘Fast’ is common between Navratre, Ramadan and Easter. It’s the power of fast (of all ten senses in the body) which takes one near to one’s consciousness and the God. Being in touch with the consciousness and the God is like reformatting once computer which removes all the temporary files and bad sectors (sins).

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